Test kit taken apart SHBG: sex hormone binding globulin (SHBG) for the analysis of a comprehensive guide

Sex hormone binding globulin (SHBG) in the human body is an important protein that plays a critical role in maintaining the hormonal balance. This protein is produced in the liver, by taking part in the preparation and transportation of the sex hormones, has a key role in the healthy functioning of the endocrine system. SHBGchanges in the levels of various hormonal disorders and may be early signs of health problems. Therefore, SHBGs measurement of processes is becoming increasingly important in clinical diagnosis and treatment. SHBG test kit taken apart, using the latest technological advancements in modern laboratory medicine, SHBG levels measured in a way that enables us to be precise and reliable, innovative diagnostic tool. In this article, SHBGbiological importance, the test kit taken apart by examining in detail the properties of SHBG and clinical applications, aims to provide a comprehensive perspective to health care professionals and interested readers.

Information about SHBG hormone taken apart

Test taken apart SHBG, sex hormone binding globulin (SHBG) levels are used to measure a reliable and sensitive method. This test plays an important role in the assessment of the health of the endocrine system. SHBG, sex hormone is a protein involved in transport and regulation. Taken apart SHBG test, in the diagnosis of various hormonal disorders, reproductive health issues in assessment and monitoring of hormonal treatments is used. High accuracy and wide measurement range, thanks to all SHBG levels can accurately measure clinically significant. In this test, cobas e series is compatible with modern devices used in laboratory environments, working provides fast and reliable results.

Sex hormone binding globulin (SHBG) what is it?

Sex hormone binding globulin (SHBG), is an important protein that plays a critical role in the human body. This protein produced by the liver, are involved in the transport and in the regulation of sex hormones in the blood around. SHBGis the main function, and the biological activity of these hormones bind to steroid hormones such as testosterone and estradiol to control.

Molecular structure and function

SHBG, has quite a complex structure at the molecular level. It is a homodimer of two identical subunits. Each sub-unit, includes special areas that can connect with a high affinity steroid hormones. In this structure, SHBGallows you to effectively connect with and move the hormones.

SHBGbasic functions are as follows:

1. Steroid hormones are transported in the bloodstream
2. Regulation of hormones and target tissues reaching
3. Free hormone levels to be checked
4. Hormone half-life extending

Binding Properties

SHBGbinding properties, is critical to understanding the functions of the endocrine system.

Relationship with testosterone and estradiol

SHBG, testosterone binds with high affinity and especially estradiole. This supplement is free of hormones in circulation and the amount of thyroid hormone has a direct effect on the biological activity. For example:

• High SHBG levels: less free testosterone and estradiol
• Low levels of SHBG more free testosterone and estradiol

This balance of the activity of the hormone in the body fine-tuning plays an important role in.

To Connect With Other Steroids

SHBG, testosterone and estradiol can be connected with other steroid hormones. Among them:

• Dihydrotestosterone (DHT)
• Androstenediol
• Dehydroepiandrosterone (DHEA)

However, SHBGand testosterone hormone is typically lower than the affinity of this ostradiole.

SHBGclinical significance

SHBGclinical significance stems from the critical role in hormone metabolism. SHBG levels, is used as an important marker in the diagnosis and monitoring of various endocrine disorders.

Symptoms Of Hormone Imbalance

SHBG levels can be an important indicator of hormone imbalances. For example:

1. High SHBG levels may be associated with:
   • Hyperthyroidism
   • Liver diseases
   • Anorexia nervosa
   • Estrogen dominance
2. This condition may be associated with low SHBG levels:
   • Hypothyroidism
   • Polycystic ovary syndrome (PCOS)
   • Obesity
   • Insulin resistance
   • Cushing’s syndrome

These symptoms may be early detection and appropriate treatment strategies in guiding the determination of hormone imbalances.

SHBGeffects on the health of

SHBGis extensive and the impact on the health of the various systems affected:

1. Reproductive health: SHBG, fertility, and has a significant impact on sexual function. Abnormal SHBG levels, and libido can be associated with infertility problems.
2. Metabolic Health: SHBG levels is inversely proportional to the risk of metabolic syndrome and type 2 diabetes. Low SHBG levels, these may be a risk factor for metabolic disorders.
3. Cardiovascular health: some studies have shown that low SHBG levels can increase the risk of cardiovascular disease.
4. Bone health: SHBG and bone mineral density is associated with. High SHBG levels, may increase the risk of osteoporosis, especially in postmenopausal women.
5. Cancer Risk: SHBG levels, hormone-dependent cancers (e.g., breast and prostate cancer) have been associated with the risk of. However, this relationship is complex and requires further research.

Why The Test Is Performed?

SHBG tests in various clinical situations and provides important information plays a critical role in the diagnosis and monitoring of hormone imbalances.

The purpose of SHBG test

The main objectives of SHBG test are as follows:

Evaluation of androgen and estrogen levels

SHBG test is used to indirectly assess free and bound testosterone with estrogen levels in the body. This evaluation is important from these aspects:

1. Understand that the actual total of cases can be misleading hormone levels hormone activity
2. Free hormone calculate the index (for example, free androgen index)
3. Monitor the effectiveness of hormone replacement therapy

Diagnosed With A Hormone Imbalance

SHBG test is done to identify the various hormone imbalances and their causes to investigate. For example:

1. Hirsutism (excessive hair growth) assess in cases of androgen excess
2. Amenorrhea (see menstruation) in cases of absence of estrogen examine
3. Libido problems, check the testosterone levels in

Polycystic ovary syndrome (PCOS) diagnosed with

SHBG test, an important aid in the diagnosis of PCOS. PCOSpatients are usually seen in Lu low SHBG levels and free testosterone levels this high can cause. SHBG test, although not included among the diagnostic criteria for PCOS, provides valuable information for treatment planning and evaluation of the syndrome.

SHBG test is done in what circumstances?

SHBG test may be requested in the specification and in various clinical situations:

Symptoms Of High Androgen

The symptoms of high androgen levels can include the following:

1. Excessive hair growth (hirsutism)
2. Acne
3. Male pattern hair loss
4. Sound thickening
5. Increase in mass Nov

These symptoms, in the presence of SHBG test to assess androgen excess may be desirable.

Symptoms Of Low Androgen

The symptoms of low androgen levels may include the following:

1. Loss of libido
2. Erectile dysfunction
3. Nov mass reduction
4. Fatigue and lack of energy
5. Depression

When observing these symptoms, SHBG, low testosterone levels can be used to assess test.

Hormonal Treatment Follow-Up

SHBG test in the monitoring of various hormonal treatments are used:

1. Hormone replacement therapy after menopause in women
2. Testosterone therapy in men
3. Women using birth control pills
4. Patients who received androgen suppressive therapy for prostate cancer

In these cases, SHBG test, and assess the effectiveness of the treatment can be done on a regular basis to monitor possible side effects.

Info About The Test Kit

Test kit taken apart SHBG, SHBG levels, which allows precise and reliable way to measure a modern diagnostic tool.

Definition Of The Test Kit

Test kit taken apart SHBG, sex hormone-binding globulin (SHBG) levels designed to measure, high-performance kit is an In Vitro Diagnostic.

Areas Of Use

This test kit is used in the following areas:

1. Clinical Laboratories: hormonal tests and evaluations for routine patient
2. Research centers: scientific studies in the field of Endocrinology and reproductive biology
3. Hospitals: in the monitoring and diagnosis of endocrine disorders
4. Specialty clinics: services of reproductive health and hormonal therapy

The Way The Test Is Done

SHBG test kit taken apart, level immunoassay (ECLIA) method uses. This method includes the following steps:

1. Sample preparation: patient’s serum or plasma is prepared for testing.
2. Antibody binding: SHBG in the example, specific antibodies are marked with.
3. The electrochemical Reaction: a reaction checked molecules is subjected to electrochemical SHBG.
4. Radiation measurement: reaction as a result of the resulting luminescence is measured.
5. The calculation of the concentration of the measured radiation is converted to the concentration of SHBG.

Features Of The Test Kit

SHBG test kit taken apart, stands out with its various features:

Sensitivity and Precision

The sensitivity and precision of the test kit features include:

1. Measuring range: 0.350-200 nmol/L
2. Analytical Sensitivity: ≤ 0.350 nmol/L
3. Functional Sensitivity: 0.800 nmol/L

All these features allows the measurement of SHBG levels are clinically meaningful.

Ease Of Use

SHBG test kit taken apart, user-friendly features:

1. Compatibility with automated systems: full integration with systems Cobas e
2. Minimal manual intervention: reducing the risk of error and improve workflow
3. Instant gratification: results in 18 minutes on average
4. Barcode system: identify the correct kit, and provides lot tracking
5. Long shelf life: 12 months under proper storage conditions can be used for

Types Of Test Kits

SHBG test kit taken apart, laboratory offers several options to suit different needs.

Different Kit Options

Kit 1

• Material Number: 03052001160
• Test Number: test 100
• Used In Devices:
  1. Cobas e411
  2. Cobas e601
  3. Cobas e602

This kit is ideal for small and medium-sized laboratories. Capacity 100 Test, Routine tests, and is suitable for medium density studies. Cobas e411, and e601 e602 compatibility with devices of different configurations provides flexibility in the laboratory.

Kit 2

• Material Number: 03052001190
• Test Number: test 200
• Used In Devices:
  1. Cobas e601
  2. Cobas e602

2 Kit, is designed for laboratories with higher testing volume. 200 test capacity, is suitable for intensive clinical laboratories and research centers. Cobas e601 e602 devices and compatibility with high throughput in environments that require efficient operation offer.

Features:

• Optimizes workflow by requiring the exchange of the kit for less
• Ideal for testing Bulk
• Offers a cost effective solution

Kit 3

• Material Number: 07258496190
• Test Number: test 300
• Used In Devices:
  1. Cobas e801

3 Kit, the highest capacity is the option to have the test, and especially in large-scale laboratories are designed for. 300 Test capacity, high-volume centers, which tests SHBG, is ideal. Cobas e801 compatibility with devices of latest technology and high automation level.

Features:

• Designed for maximum productivity
• Requires Minimum operator intervention
• It is cost effective for high volume testing
• Provides advanced quality control features

The Test Kit Is Working Devices

SHBG test kit taken apart, Roche Diagnosticscobas e series is designed to work with a variety of compatible devices. This compatibility with different volume laboratory needs and can respond to their business.

Compatible Device Models

Cobas e411

Cobas e411, a compact design and is an ideal device for small and medium-sized laboratories.

Features:

• 86 per hour you can speed up the test
• Shelves and cassette versions available
• Ability to work in 18 different tests at the same time
• Robust design that requires minimal maintenance

Cobas e601

Cobas e601, medium and large laboratories designed for high-performance device.

Features:

• You can speed up the test 170 per hour
• Thanks to the modular design, the ability to integrate with other devices cobas
• 25 different test at the same time until the capacity to work
• Advanced automation features

Cobas e602

Cobas e602, e601test capability allows the improved version and higher.

Features:

• You can speed up 200 Tests per hour
• Advanced reactive management
• More extensive test menu
• High-precision measurement technology

Cobas e801

Cobas e801, highest capacity and most advanced on the cobas e-series device.

Features:

• 300 tests per hour with exceptional speed, which can be long
• Ability to work in 48 different tests at the same time
• Advanced automation and integration capabilities
• Intelligent design requires minimal operator intervention

Cobas e402

Cobas e402, designed for laboratories, medium-sized, with a device that acts as a bridge between e601 e411.

Features:

• 90 Tests per hour you can speed up
• Compact design
• Ability to work up to 20 different tests at the same time
• Flexible working mode options

Each of these devices, is designed to work in perfect harmony with the SHBG test kit taken apart, thus most appropriate to the needs of laboratories can obtain optimum performance and efficiency by selecting the device.

Frequently asked questions (FAQ)

In this section, SHBG test kit taken apart about the most frequently asked questions and their answers have been given.

If Cobas test kit replacement reagents for SHBG taken apart if you want to get information, you can contact the following contact details!

Address: Orucreis Tekstilkent Street Tekstilkent Site No:196 D:G2 Block, 34235 Esenler/Istanbul

Phone: (0212) 4384542

Mail: [email protected]