Roche DNA sample preparation kit

Cobas DNA sample preparation kit, cobas systems genomics and oncology that is designed to be used in conjunction with a special solution. Especially FFPET (formalin-fixed, paraffin-embedded tissue) samples have been developed for the purpose of preparation of the manual. By doing this in a lab environment sensitive DNA isolation kit allows you to carry out accurate and reliable genetic analyses.

Cobas BRAF mutation test cobas DNA sample preparation kit cobas EGFR mutation, KRAS mutation testing and genetic tests such as the test works in a way that is compatible with. These tests are especially important tools in the assessment of mutations in cancer are among the oncology field.

BRAF, EGFR and KRAS mutations in the diagnosis of various types of cancer and plays a critical role in treatment planning. For this reason, accurate and reliable DNA isolation of the process be done in a manner that it is important.

What is the Roche DNA kit?

Roche DNA kit, DNA isolation and molecular genetic research laboratory that provides diagnostic applications developed for high purity and reliable product. Clinical diagnosis, oncology, infectious diseases, it is widely used in the fields of biotechnology and pharmacogenetic analysis.

This kit is especially biological samples from various formalin-fixation and paraffin-embedded tissue (FFPET) blood plasma, saliva, and is optimized to obtain highly efficient cellular materials, such as samples DNA.

Roche DNA kits compatible with manual and automatic systems laboratories gives you the possibility to use flexible and practical. Kits for automated systems that are compatible with high volume makes it possible to work with a sample and save time. At the same time, the manual method for laboratories that work with user-friendly by providing simplifies the process of DNA isolation protocols.

Roche DNA kit

Cobas DNA sample preparation kit is an advanced solution that provides rapid and efficient isolation of DNA for genetic testing. Especially formalin-fixation and paraffin-embedded tissue (FFPET) shows high performance. Molecular diagnostic applications in clinical research and is optimized to obtain reliable results. The highlights of the kit is given below.

• <3 hours FFPET genomic DNAseparates from.
• FFPET sections cobas mutation test can provide enough DNA to perform only a 5 µm.
• DNA isolation from up to 24 samples at the same time a sufficient amount of reagent contains possible.

Roche’s thanks to innovative technology, this kit improves the reliability of precise genetic analysis while minimizing the risk of contamination. Thanks to reliable structure, and Mutation Testing in the lab and can be easily applied to molecular biology techniques such as PCR is an ideal solution for qPCR.

Areas Of Use

Roche Cobas DNA sample preparation kit, advanced genetic research and molecular diagnostic tests used in DNA isolation system. Especially designed for DNA isolation from ffpet samples. This improves the reliability of genetic testing kit to obtain the DNA providing a variety of high purity. The fields of use of the kit are as follows.

• Cancer Research, BRAF, EGFR and KRAS gene mutations, such as are used to detect.
• Plays a role in diagnosis of genetic diseases and individualized treatment approaches.
• Polymerase chain reaction (PCR) – based DNA tests provides high quality.
• The genetic profile of patients according to the regulation of drug therapies support.
• In the fields of genetics and biotechnology used in the preparation of the DNA samples is preferred.

The cobas EGFR mutation test v2

Cobas EGFR mutation test v2, epidermal growth factor receptor (EGFR) gene mutations, which can detect sensitive and reliable real-time PCR test. In this test, the EGFR gene, 18, 19, 20 and 21. analyzes and T790M resistance mutations in cancer treatment particularly like the mutations by mutation plays a critical role in the process.

EGFR mutations, especially in small cell lung cancer (NSCLC) in their approach to diagnosis and personalized treatment of diseases such as is of great importance.

This test lab work with both tissue and plasma samples were developed to simultaneously and enables you to analyze different sample types. In this way, to follow the course of the disease and to determine appropriate treatment options becomes a lot easier.

Roche has developed a kit to optimize the workflow cfDNA sample preparation of the test. This kit for DNA isolation from plasma samples in the most efficient manner by performing the analysis process more credible.

Cobas KRAS Mutation Test

Cobas KRAS mutation test, developed to identify KRAS gene mutations in colorectal cancer patients sensitive molecular diagnostic test. This test is especially anti-EGFR monoclonal antibody therapy will support identification of patients with a high risk of unresponsive.

Mutations in the KRAS gene is an important determinant of treatment options and personalized treatment of cancer, it is crucial for the determination.

KRAS the KRAS gene mutation testing of 12, 13 and 61. major is able to detect mutations in codons. In this way, it helps in determining the appropriate treatment approach in patients with colorectal cancer.

Test, formalin-fixed, paraffin-embedded tissue (FFPET) are designed to work, and the wild-type DNA in an environment that contains <5% mutant copies of the series can detect.

• Codons 12, 13 and 61 in major mutations detected.
• <5% of mutant copies of the series detects.
• <8 hours the test is complete.
• >10% of tumor ffpet sections with only 5 µm with a content analysis is performed.
• In liquid form ready-to-use reagents provide practice with.
• Automated reporting system that speeds up the process and reduces the margin of error is there.

Cobas 4800 BRAF V600 mutation Test

Cobas 4800 BRAF V600 mutation test, formalin-fixed, paraffin-embedded (FFPET) is a test developed to detect BRAF V600 mutations in human tissue sensitive and reliable PCR.

Testing, especially in patients with BRAF gene mutations is designed to help identify melanoma tumors. At the same time, papillary thyroid carcinoma (PTC) are used to detect BRAF V600 mutations in patients.

Carrying this mutation BRAF V600 mutation has a significant effect on the progression of cancer and targeted therapies for patients who are appropriate candidates. Test this by playing a critical role in a personalized medicine approach to cancer treatment will contribute to the process.

• In melanoma, BRAF mutations account for 90% of which detects the mutation V600E. V600D V600K mutations and also others, such as V600E2 is also detected.
• FFPET tissues in ≥5% of BRAF mutation V600E mutation detects level.
• Tumors with BRAF V600 mutations was used to identify patients in clinical trials is important.
• After sampling <8 hours the test is complete.
• In one study, an efficient process for large samples analysis laboratories presents that can handle maximum 94.

Frequently Asked Questions