ASTL testie Aspartate Aminotransferase measurement is an important biochemistry test that is often used in the diagnosis of liver and muscle damage. This test, IFCC according to the method, without pyridoxical phosphate activation performed. Specifically serum and plasma This test, which has been studied with examples, provides reliable data in biochemical analysis of diseases.
IFCC By Method ASTL Clinical Importance of Test
Aspartate Aminotransferase (AST)It is an important enzyme that is mainly found in liver, heart and muscle tissues. ASTL test, EC 2.6.1.1 (L-aspartate: 2-oxoglutarate aminotransferase) measuring the activity. This method made without the activation of pyridoxical phosphate is preferred especially in routine screenings and general liver health assessments.
Which Systems Compatible?
ASTL test, Roche Diagnostics’s fully compatible with the following device platforms:
- cobas c 111
- cobas c 311
- cobas c 501
- cobas c 502
- COBAS INTEGRA 400 News
Thanks to these systems, the laboratory integration of the test is easy and the results are obtained with high precision.
Pyridoxical Phosphate Non-Smoking AST Advantages of Measurement
Made without Pyridoxical phosphate activation ASTL Applicationsmay be more suitable in some patient groups. Vitamins B6 deficiency or in certain clinical cases, this method is preferred. Also, in some laboratories provision of standardization In terms of pyridoxical phosphorus method is more common.
COBAS INTEGRA systems and systems active (PYP with) both non-activated (ASTL) forms can be used separately. But only in this content pyridoxical without phosphate ASTL The application was discussed.
Regulatory Information
ASTL test, only in vitro diagnosis designed for use for purpose. Clinical decisions should be evaluated as a supporter.
