About the product
ALTL is an in vitro diagnostic reagent from Roche Diagnostics for the measurement of alanine aminotransferase (ALT). Its full name on Roche’s product page is alanine aminotransferase according to IFCC without pyridoxal phosphate activation.
According to Roche, the test is for the quantitative determination of ALT in human serum and plasma. The product is part of the Roche Diagnostics test kit range supplied by Tilia Medical.
According to Roche, the Method Sheet covers the ALT application without pyridoxal phosphate activation on cobas c systems. The compatible products section on the Roche page is empty, and the technical documents section has not been loaded.
Measured parameter and clinical significance
ALT is an enzyme found mainly in the liver. According to MedlinePlus, it is normally present in the blood at low levels; when liver cells are damaged it enters the blood and the value rises.
MedlinePlus states that the ALT test is used to diagnose liver damage or disease and can detect some liver conditions before symptoms appear. The test is requested in routine checkups, for symptoms such as jaundice or abdominal swelling, and in people with heavy alcohol use, obesity, diabetes or exposure to hepatitis. The result is interpreted together with other liver tests and personal factors.
Technical information
- Sample type (Roche): human serum and plasma
- Method (Roche): according to IFCC, without pyridoxal phosphate activation
- Analyzers (Roche): cobas c 311, cobas c 501, cobas c 502, COBAS INTEGRA 400 plus
- Pack size (Roche): 500 tests (cobas c 311/501/502)
- Measuring range: not stated for ALTL on the Roche page. The numerical range on the page belongs to the ALTPL product, which uses pyridoxal phosphate activation
Use and compatibility
The Roche page associates ALTL with the cobas c 311, 501, 502 and COBAS INTEGRA 400 plus. The ALT product with pyridoxal phosphate activation has a separate test code; the requested method must be specified when ordering.
For product, quotation and technical information requests, use the contact form or write to info@tiliamedical.com.
On the Roche page, the product number for ALTL is given as 20 764 957 322 and the product code as CPS_000020. The 500-test pack is for the cobas c 311/501/502. For aspartate aminotransferase measurement, see the ASTL test kit page; according to MedlinePlus, AST and ALT tests are often requested together with other liver function tests.
Frequently asked questions
No. According to Roche’s page, ALTL is the method that works without pyridoxal phosphate activation. The method with activation is a separate product with the code ALTPL.
According to Roche, it is used with human serum and plasma.
According to MedlinePlus, ALT is found mainly in the liver. It enters the blood when liver cells are damaged.
