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A chemistry analyzer runs tests that measure liver and kidney indicators, glucose, proteins and electrolytes in serum or plasma. According to MedlinePlus, the comprehensive metabolic panel also checks these parameters. The models offered by Tilia Medical are the following: cobas c 111, cobas c 303, cobas 6000, cobas Integra 400 Plus and Beckman Coulter DxC 500i.
According to Roche, the c 111 is a continuous, random-access analyzer. It performs photometric analysis on serum, plasma, urine and, for HbA1c, whole blood; it is optimized for small workloads of up to 50 samples per day and is not designed for point-of-care testing. According to Roche, the cobas 6000 combines photometric analysis with ISE in the c 501 module.
Hormones, cardiac markers and infection tests are mostly measured by immunoassay. According to MedlinePlus, the TSH test shows how well the thyroid is working, but it does not show the cause of a thyroid problem. Tilia Medical’s product range includes Roche immunoassay units such as the cobas e 402 and cobas e 411. According to Roche package inserts, Elecsys tests are described as ECLIA, that is, electrochemiluminescence immunoassay, and run on cobas e analyzers. According to Roche, the cobas pure solution combines the c 303 and e 402 analytical units with a sample supply unit.
According to Abbott, the Alinity i is a compact immunoassay system that uses CHEMIFLEX chemiluminescence detection technology.
An arterial blood gas test measures the amount of oxygen and carbon dioxide in the blood. According to MedlinePlus, these measurements are used to evaluate how well the lungs take in oxygen and remove carbon dioxide. An electrolyte panel examines sodium, potassium and chloride as well as carbon dioxide.
According to Medica, the EasyBloodGas measures pH, PCO2 and PO2 and calculates 11 additional parameters. The EasyStat adds sodium, potassium, calcium and chloride to these, as well as hematocrit. According to OPTI Medical, the CCA-TS2 model works with optical fluorescence technology that uses no electrodes or contact points, and analyzes whole blood, plasma or serum with a single-use cassette. This product group also includes the EDAN i20 and OPTI CCA and CCA-TS pages.
These two instrument groups are not used for the same purpose. Blood gas instruments measure gas parameters (pH, PCO2, PO2) and mostly electrolytes as well; for example, the Medica EasyStat measures pH, PCO2, PO2, sodium, potassium, calcium, chloride and hematocrit. Chemistry analyzers run many clinical chemistry parameters by photometric methods. One does not replace the other.
OPTI Medical describes the CCA-TS2 as using optical fluorescence technology with no electrodes or contact points, and a single-use cassette.
According to Beckman Coulter’s technical summary, the DxC 500i runs 400 photometric tests per hour; with ISE this rises to 800. On the immunoassay side, throughput is 100 tests per hour. It is recommended to confirm current values with the manufacturer before purchase.