About the product
The COBAS INTEGRA 400 plus is a clinical chemistry analyzer from Roche Diagnostics. Roche lists the instrument, together with the cobas c 111, c 311, c 303, c 501, c 502, c 503, c 701 and c 702, among the platforms in the parameter list it has prepared for the serum work area. For brand information, the Roche Diagnostics page can be consulted.
System features
The information below is based on Roche’s parameter list updated in March 2024 and on Roche reagent product pages. Roche states that product availability may vary from country to country and that the availability of tests should be verified with the local Roche representative. The test groups below are examples marked in the COBAS INTEGRA 400 plus column of the list.
- Anemia: ferritin, iron, transferrin
- Bone: calcium, phosphorus
- Cardiac: cholesterol, HDL cholesterol (direct), CK, CK-MB, hs CRP
- Metabolic: glucose, lactate, magnesium, sodium, potassium, chloride, triglycerides
- Kidney: creatinine (enzymatic and Jaffe), urea/BUN, uric acid, albumin
- Hepatology: ALT, AST, ALP (IFCC), total and direct bilirubin, GGT
- Inflammation: CRP, IgA, IgG, IgM, rheumatoid factor, haptoglobin
- Therapeutic drug monitoring: phenobarbital, phenytoin, salicylate, valproic acid, vancomycin
- Drugs of abuse: amphetamine, barbiturate, benzodiazepine, cannabinoid, cocaine, opiate
Technical information
- Product class: clinical chemistry analyzer, serum work area (Roche parameter list)
- Packs listed on Roche product pages: 300 tests for CA2 Gen.2, 350 tests for HDLC4, 200 tests for CK
Use and compatibility
Roche reagent product pages list the Roche CA2 Gen.2 calcium, HDLC4 HDL cholesterol and CK creatine kinase reagents for the COBAS INTEGRA 400 plus. The same reagents are also listed for the cobas c 111 and cobas c 303; details are on the cobas c 111 and cobas c 303 pages.
For product, quotation and technical information requests, the form on the contact page or info@tiliamedical.com can be used.
Frequently asked questions
According to the Roche parameter list, the instrument covers anemia, bone, cardiac, metabolic, kidney, hepatology and inflammation tests, as well as therapeutic drug monitoring and drugs of abuse tests. Availability may vary by country.
Roche product pages list the CA2 Gen.2 calcium, HDLC4 HDL cholesterol and CK reagents for the COBAS INTEGRA 400 plus. The packs are 300, 350 and 200 tests respectively.
No. The Roche parameter list states that product availability may vary from country to country and that tests should be checked with the local Roche representative.
