About the product
The cobas e 402 analytical unit is Roche Diagnostics’ fully automated analyzer for immunology tests. According to Roche’s product description, the instrument is designed for quantitative and qualitative in vitro tests, including cobas e flow tests, and is used for in vitro diagnostic purposes only. The unit is also part of Roche’s cobas pure integrated solutions system as the immunochemistry unit. For general information on the brand, the Roche Diagnostics page can be consulted.
System features
Measurement is based on electrochemiluminescence (ECL) technology for heterogeneous immunoassays. Roche reports that the unit runs up to 120 tests per hour and states that actual throughput varies with the test mix requested per sample. The instrument has 28 reagent positions. Reagent packs are recognized by RFID. Roche states that the unit occupies 1.2 square meters.
Technical information
- Measurement principle: ECL technology for heterogeneous immunoassays (manufacturer's claim)
- Throughput: up to 120 tests per hour, depending on the test mix (manufacturer's claim)
- Reagent system: manually loaded cobas e pack green packs, RFID recognition, 28-pack disk, storage at 5 to 10 °C (manufacturer's claim)
- Sampling: 30-second cycle, pipetting volume of 4 to 60 µL in 1 µL steps, liquid level, clot and air aspiration detection (manufacturer's claim)
- Reaction system: 38 incubator positions, 120 µL reaction volume, 37 °C ± 0.3 °C temperature, reaction times of 9, 18 or 27 minutes (manufacturer's claim)
- Measuring cell: a single ECL measuring cell (manufacturer's claim)
- On-board reagent stability: up to 4 months depending on the test (manufacturer's claim)
- Sample types: serum and plasma, urine, cerebrospinal fluid, whole blood, oral fluid, hemolysate and amniotic fluid (list on the Roche product page)
Use and compatibility
The cobas e 402 runs Elecsys tests developed for cobas e immunoassay analyzers. On Roche’s product pages, the Elecsys Rubella IgM and Elecsys Vitamin B12 II tests are listed as compatible with this instrument. Roche states that the cobas pure integrated solutions system consists of a sample supply unit and up to two analytical units. In this system, the e 402 unit offers more than 100 immunoassays and 9-minute STAT applications. The conditions of use for each test are given on the relevant method page.
For product, quotation and technical information requests, the form on the contact page or info@tiliamedical.com can be used.
Frequently asked questions
According to Roche, the unit runs up to 120 tests per hour. Actual throughput varies with the test mix requested per sample.
According to Roche, the instrument uses electrochemiluminescence (ECL) technology for heterogeneous immunoassays. Measurement is performed in a single ECL measuring cell.
According to Roche, cobas pure integrated solutions consists of a sample supply unit and up to two analytical units. The e 402 is the immunochemistry unit, and the c 303 is the clinical chemistry and ISE unit.
