About the product
CRPHS (Cardiac C-Reactive Protein (Latex) High Sensitive) is an in vitro diagnostic reagent from Roche Diagnostics for high-sensitivity CRP measurement. According to Roche, the test is used on cobas c systems for the quantitative determination of C-reactive protein (CRP) in human serum and plasma.
The term Latex in the product name indicates that the reagent is latex-based. The product is part of the Roche Diagnostics test kit range supplied by Tilia Medical.
Measured parameter and clinical significance
CRP is a protein produced by the liver in response to inflammation. According to MedlinePlus, a standard CRP test shows the level of inflammation caused by disease, injury or chronic conditions, but it does not show the cause or location of the inflammation.
The high-sensitivity CRP (hs-CRP) test measures the same protein but detects very small increases in CRP level. MedlinePlus states that hs-CRP is used to estimate the risk of heart disease. High-sensitivity reagents such as CRPHS are therefore aimed at the low-level range that standard CRP tests cannot measure.
MedlinePlus states that for the standard CRP test, healthy levels are generally about 0.8 to 1.0 mg/dL or below. The standard test is also used to monitor infection after surgery, to follow treatment and to inform decisions related to sepsis.
Technical information
- Sample type (Roche): human serum and plasma
- Analyzers (Roche): cobas c 111; cobas c 303/503/703; cobas c 701/702; cobas c 311/501/502 and COBAS INTEGRA 400 plus
- Pack size (Roche): 250 tests (cobas c 701/702); 600 tests (cobas c 303/503/703); 300 tests (COBAS INTEGRA 400 plus and cobas c 311/501/502); 2 x 50 tests (cobas c 111)
- Measuring range and method details: not stated on the Roche product page; the only method information is the term Latex in the product name
Use and compatibility
On Roche’s product page, CRPHS is listed with four pack types across the cobas c and COBAS INTEGRA families. The same family also includes a separate Roche Tina-quant product for high-sensitivity CRP; the product code and analyzer match should be confirmed when ordering.
For product, quotation and technical information requests, use the contact form or write to info@tiliamedical.com.
Frequently asked questions
According to Roche, it works with human serum and plasma.
According to MedlinePlus, the standard CRP test assesses inflammation. The hs-CRP test measures very small increases in CRP and is used to estimate the risk of heart disease.
The Roche page lists the cobas c 111, cobas c 303/503/703, cobas c 701/702, cobas c 311/501/502 and COBAS INTEGRA 400 plus.
