About the product
Elecsys Cortisol III Urine (Roche code PID00000511) is an immunoassay used for the in vitro quantitative determination of cortisol in human urine. The Roche product page names the method as electrochemiluminescence immunoassay (ECLIA) and states that cortisol measurement is used in the diagnosis and management of adrenal gland functional disorders.
Measured parameter and clinical significance
According to MedlinePlus, cortisol is a hormone produced in the adrenal glands. It contributes to the response to stress, the reduction of inflammation, the regulation of blood sugar and metabolism, and the control of blood pressure. Because part of the cortisol passes into the urine, the level in urine gives an estimate of the level in blood.
According to MedlinePlus, the urine cortisol test is requested mainly to investigate conditions of cortisol excess such as Cushing’s syndrome and to monitor treatment of these conditions. The sample is most often taken as a 24-hour urine collection. In some cases a single morning urine is used. The same source states that the test alone cannot determine the cause of abnormal levels and that follow-up tests are usually needed. Long-term steroid use or sudden withdrawal of steroids is the most common cause of an abnormal result. Stress, pregnancy and exercise can also affect the cortisol level.
MedlinePlus associates low cortisol with Addison’s disease and with secondary adrenal insufficiency of pituitary origin. Temporarily high cortisol can occur with depression, anxiety, alcohol use disorder, poorly controlled diabetes or obesity. The person being tested should tell the healthcare provider about all medicines in use, including skin creams.
Technical information
- Product: Elecsys Cortisol III Urine (Roche, PID00000511)
- Method: electrochemiluminescence immunoassay (ECLIA)
- Sample: human urine
- Pack size: 100 tests
- Sample volume, test time and measuring range are in the Roche method sheet
Use and compatibility
The Roche product page lists these systems:
- cobas e 411
- cobas e 601
- cobas e 602
System page: cobas e 411. Other hormone parameters are listed in the hormone test kits category.
Urine collection conditions and preparation depend on the instructions of the healthcare facility requesting the test.
Frequently asked questions
According to the Roche product page, the test is defined for the determination of cortisol in human urine.
According to MedlinePlus, the sample is most often taken as a 24-hour urine collection. In some cases a single morning urine is used.
According to MedlinePlus, the test alone cannot determine the cause of abnormal levels, and follow-up tests are usually needed.
Contact
For product, quotation and technical information requests, use the contact form or write to info@tiliamedical.com.
