About the product
Elecsys Anti-Tg (Roche code CPS_000443) is an immunoassay used for the in vitro quantitative determination of thyroglobulin antibodies in human serum and plasma. The Roche product page specifies the method as electrochemiluminescence immunoassay (ECLIA) and defines the test for cobas e immunoassay analyzers.
Measured parameter and clinical significance
According to MedlinePlus, thyroglobulin is a protein involved in making thyroid hormones, and Tg antibody tests look for antibodies formed against this protein. The test is usually requested when T3, T4 or TSH results suggest hypothyroidism or hyperthyroidism, to investigate whether the cause is an autoimmune disease. It can also be used when symptoms point to Hashimoto’s or Graves’ disease, or when screening high-risk groups such as women, adults over 50 and people with a family history of thyroid disease.
According to the same source, a high Tg antibody level is an indicator of Hashimoto’s disease. In evaluating Graves’ disease, other antibody tests such as TSI and TRAb are more prominent. MedlinePlus describes Hashimoto’s disease as the most common cause of hypothyroidism and Graves’ disease as the most common cause of hyperthyroidism. The source states that results are interpreted together with symptoms, other test results and medical history, and that a single result does not prove an autoimmune disease. A blood sample is taken for the test, and no special preparation is needed.
Technical information
- Product: Elecsys Anti-Tg (Roche, CPS_000443)
- Method: electrochemiluminescence immunoassay (ECLIA)
- Sample: human serum and plasma
- Pack size: 100 and 300 tests (cobas e 402 and cobas e 801)
- Pack size: 100 tests (cobas e 411, cobas e 601 and cobas e 602)
- Sample volume, test time and measuring range are in the Roche method sheet
Use and compatibility
The Roche product page lists these systems:
- cobas e 402 and cobas e 801
- cobas e 411
- cobas e 601 and cobas e 602
System pages: cobas e 411 and cobas e 402. Thyroid and other hormone parameters are listed in the hormone test kits category.
Frequently asked questions
According to the Roche product page, the test quantitatively measures thyroglobulin antibodies in human serum and plasma.
According to MedlinePlus, the test is usually requested when other thyroid tests suggest hypothyroidism or hyperthyroidism, to investigate whether the cause is autoimmune.
According to MedlinePlus, a high Tg antibody level is an indicator of Hashimoto’s disease, and a result alone does not prove a disease.
Contact
For product, quotation and technical information requests, use the contact form or write to info@tiliamedical.com.
