About the product
Elecsys FT4 IV (Roche code PID00000019) is a test used for the in vitro quantitative determination of free thyroxine (FT4) in human serum and plasma. The Roche product page specifies the method as electrochemiluminescence immunoassay (ECLIA) and defines the test for cobas e immunoassay analyzers.
Measured parameter and clinical significance
According to MedlinePlus, free T4 measures only the active hormone that reaches the tissues. Total T4 measures free and protein-bound T4 together. MedlinePlus states that experts regard free T4 as more accurate and that it is therefore used more often.
According to the same source, a T4 test may be requested to evaluate symptoms of hypothyroidism and hyperthyroidism, to examine thyroid nodules and goiter, to investigate pituitary and hypothalamic disorders, in newborn screening and to check the effect of thyroid hormone treatment. The test alone does not define thyroid disease and is usually interpreted together with TSH and other thyroid tests. Severe illness, some medicines and supplements can affect the levels.
MedlinePlus associates low T4 with hypothyroidism, Hashimoto’s disease, pituitary problems and iodine imbalance. High T4 can be associated with hyperthyroidism, Graves’ disease, toxic nodules, excess iodine and excess use of thyroid medicine. The physician should be told about all medicines and supplements in use.
Technical information
- Product: Elecsys FT4 IV (Roche, PID00000019)
- Method: electrochemiluminescence immunoassay (ECLIA)
- Sample: human serum and plasma
- Pack size: 100, 200 and 300 tests (listed by system on the product page)
- Sample volume, test time and measuring range are in the Roche method sheet
Use and compatibility
The Roche product page lists these systems:
- cobas e 402 and cobas e 801
- cobas e 411
- cobas e 601 and cobas e 602
- one list also includes the cobas smart e
System pages: cobas e 411 and cobas e 402. Thyroid and other hormone parameters are listed in the hormone test kits category.
Which pack applies to which system should be confirmed from the ordering information on the Roche product page.
Frequently asked questions
According to the Roche product page, the test quantitatively measures free thyroxine in human serum and plasma.
According to MedlinePlus, free T4 measures only the active hormone that reaches the tissues, while total T4 measures free and protein-bound T4 together.
According to MedlinePlus, a T4 test alone cannot define thyroid disease and is usually interpreted together with TSH and other thyroid tests.
Contact
For product, quotation and technical information requests, use the contact form or write to info@tiliamedical.com.
