About the product
CHOL2 (Cholesterol Gen.2, Roche code CPS_000069) is an in vitro diagnostic test used for the quantitative determination of cholesterol in human serum and plasma. According to the Roche product page, the test is used on cobas c systems and on the COBAS INTEGRA 400 plus.
Measured parameter and clinical significance
According to MedlinePlus, total cholesterol is the total amount of LDL and HDL cholesterol in the blood and is one of the values of the lipid panel. Besides total cholesterol, the panel includes LDL, HDL and triglycerides. The test helps estimate the risk of heart disease. Because total cholesterol alone does not show the LDL and HDL ratio, the full panel gives more information.
MedlinePlus states that a total cholesterol value below 200 mg/dL is considered healthy in adults. The same source notes that age, family history, lifestyle and other risk factors affect interpretation and that evaluation rests with the healthcare professional. In some cases, fasting for 9 to 12 hours may be required for the test.
Technical information
- Product: CHOL2, Cholesterol Gen.2 (Roche, CPS_000069)
- Analyte and sample: cholesterol; human serum and plasma
- Method: the FDA 510(k) summary that Roche prepared for COBAS INTEGRA Cholesterol Gen.2 describes an enzymatic colorimetric method using cholesterol esterase, cholesterol oxidase and peroxidase, and a red quinone imine dye directly proportional to the cholesterol concentration (manufacturer's statement). Method details for cobas c systems are in the Roche method sheet
- Pack size: CHOL2 2,600 tests (cobas c pack green)
- Pack size: 4 × 100 tests (cobas c 111)
- In the ordering table of the product page, packs of 400 and 2,100 tests are listed under the name CHOL HiCo Gen.2
Use and compatibility
The Roche product page lists these systems:
- cobas c 111
- cobas c 303, 503 and 703
- cobas c 311, 501 and 502
- cobas c 701 and 702
- COBAS INTEGRA 400 plus
System pages: cobas c 111 and cobas c 303. A relevant page is available for the COBAS INTEGRA 400 plus. Other lipid and biochemistry parameters are in the biochemistry test kits category.
For measuring range and calibrator information, refer to the current Roche method sheet.
Frequently asked questions
According to the Roche product page, the test is defined for cholesterol determination in human serum and plasma.
The FDA 510(k) summary that Roche prepared for COBAS INTEGRA Cholesterol Gen.2 describes an enzymatic colorimetric method with cholesterol esterase, cholesterol oxidase and peroxidase.
According to MedlinePlus, total cholesterol is the total amount of LDL and HDL cholesterol in the blood and is a value of the lipid panel that helps estimate the risk of heart disease.
Contact
For product, quotation and technical information requests, use the contact form or write to info@tiliamedical.com.
